唑吡坦
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Oral |
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70% (oral) 92% bound in plasma |
Hepatic - CYP3A4 |
2.5 to 3 hours |
56% 经尿液,34% 经粪便 |
IUPAC命名法
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82626-48-0 |
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100.115.604
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C19H21N3O |
307.395 g/mol |
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SMILES
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唑吡坦(英語:Zolpidem)是一種Z-drugs安眠藥,其藥發時間約在三十分鐘之內,藥效維持兩至三小時。市場上常見的藥名包括、Adormix、Ambien、Ambien CR、Edluar、Damixan、Ivedal、Nytamel、Stilnoct、Stilnox、Sucedal、Zoldem、Zolnod及Zolpihexal等[1][2][3][4],中國大陸商品名為思諾思(英語:Stilnox),台灣則有佐沛眠(英語:Zolpium)、使蒂諾斯等名稱。
唑吡坦可以迅速从肠胃道吸收;Tmax=0.5-3小时;口服生物利用度70%,副作用是夢遊。
参考资料[编辑]
- ^ Ambien.com. AMBIEN Prescribing Information. Information About a Short-term Treatment for Insomnia - Ambien.com Home Page for Health-care Professionals. Sanofi-Synthelabo Inc. New York, NY 10016. 2004 [2005-06-27]. (原始内容存档于2005-06-27).
- ^ STILNOX (zolpidem tartrate) PRODUCT INFORMATION (页面存档备份,存于互联网档案馆) Sanofi-Synthelabo Australia Pty Limited. April 15, 2004
- ^ sanofi-aventis : Drugs and Products - CNS - Stilnox/Ambien/Myslee. 2006-11-07 [2006-11-22]. (原始内容存档于2007-09-27).
- ^ Benzodiazepine Names. (原始内容存档于2008-12-08).
外部連結[编辑]
- 医学主题
- Zolpidem. Drug Information Portal. U.S. National Library of Medicine. [2020-10-22]. (原始内容存档于2020-11-27).
- Man who couldn't talk or move for 8 years 'wakes up' 20 minutes after docs gave him sleeping drug(页面存档备份,存于互联网档案馆)
template:Insomnia pharmacotherapies(英语:template:Insomnia pharmacotherapies) template:GABAAergics(英语:template:GABAAergics)
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